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Over the last decade, translational research has developed into a science that involves various “scientific and engineering disciplines, medicine, team science, project management and partnership development with industry," [1]. It vows to accelerate diagnostics and therapies into patient care by bringing discoveries across the fundamental, proof-of-concept, and development stages [1]. Researchers, scientists, and engineers from academia and industry must be engaged at proper stages to achieve success [1].
In its production of original research, biomedical optics and biophotonics have developed laser surgery, light-activated therapies, optical diagnostics and imaging, and light-based technologies for monitoring and manipulating biological processes in the body [1]. In translational research, models have been developed to drive forward the translation process, support problem-driven research, and provide innovative training programs [1]. There are still many challenges to overcome despite the rising recognition and support of translational research [1]. The marketing of diagnostics and treatments to reduce the burden of human diseases requires collaboration between academia and industry [1].
In 2017, a symposium was held by the Human Toxicology Project Consortium of the Humane Society of the United States in conjunction with the Health Law, Policy & Ethics Project at Emory University School of Law [2]. The symposium showcased “innovations using human-based in silico and in vitro models for drug and device discovery," [2].The development of biomedical technologies such as human-on-a-chip technology will enhance science, make medical treatments more efficient, and reduce animal use [2]. The FDA recognizes that animal testing rarely translates into safe, effective drugs for humans [2].
Translational research will serve as a critical part in bringing better, more cost effective treatments and diagnostics to patients [1]. Along with the constant advances in biomedical optics and photonics technology, scientists and engineers will “have tremendous opportunities to engage with clinicians and patients and establish solid partnerships with industry," [1]. Furthermore, a new generation of scientists, engineers, and clinicians can collaborate with industry professionals to tackle problems in medicine and human health with the help of training programs in translational sciences [1].
References:
1. Raff, A. B., Seiler, T. G., & Apiou-Sbirlea, G. (2017, November 3). Bridging Medicine and biomedical technology: Enhance translation of fundamental research to patient care. Biomedical optics express. Retrieved February 20, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745088/
2. Benam, K. H., Gilchrist, S., Kleensang, A., Satz, A. B., Willett, C., & Zhang, Q. (2019, April 4). Exploring new technologies in biomedical research. Drug Discovery Today. Retrieved February 20, 2022, from https://www.sciencedirect.com/science/article/pii/S135964461830518X
Contributors:
Author: Rayven Hall
Editor: Sara Giarnieri
Health scientist: Rayven Hall